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Explore Infectious Disease via the Disease Triangle Start Exploring
Host (Human and Model Organisms)
Host-Pathogen Interactions
Host-Vector Interactions
Pathogen-Vector Interactions
News & Announcements from the BRCs
Release VB-2014-10

24 Oct 2014-VectorBase

We are pleased to announce the October release of VectorBase (VB-2014-10): New gene sets for four Glossina species (Glossina austeni, Glossina brevipalpis,... click to see more
15 Oct 2014-ViPRStandardized Metadata for Human Pathogen/Vector Genomic Sequences.
6 Oct 2014-IRDNext IRD Release
11 Sep 2014-PATRICComparative Genomic Analysis at PATRIC, A Bioinformatic Resource Center. Book chapter in Host Bacterial Infections, Methods in Molecular Microbiology.
5 Sep 2014-EuPathDB25th Molecular Parasitology Meeting - September 14-18, 2014
12 Dec 2013-Pathogen PortalHost Response Data Updated
About the Pathogen Portal
The Pathogen Portal supports and links to five Bioinformatics Resource Centers (BRCs). Each BRC specializes in a different group of pathogens, focusing on, but not limited to, pathogens causing (Re-)Emerging Infectious Diseases, and those in the NIAID Category A-C Priority Pathogen lists for biodefense research. The scope of the BRCs also includes Invertebrate Vectors of Human Disease.

In addition to supporting, and serving as an entryway to, the BRCs, the Pathogen Portal's scientific focus is integrating host-response data that span the pathogens and vectors supported by the BRCs, thereby moving towards an integrative view of Host-Pathogen-Environment interactions, also known as the Disease Triangle. Originating from plant pathology, the concept of the Disease Triangle provides an ecological view of disease which is increasingly relevant to the Health Sciences. According to this view, disease arises when three criteria are met: an infectious Pathogen; a susceptible Host, and a conducive (to disease) Environment. Because some diseases include invertebrate Vectors as part of their ecology, the Disease Triangle broadly considers Vectors to be a component of the Environment.

The Pathogen Portal is developed and maintained by the CyberInfrastructure Division at the Virginia Bioinformatics Institute at Virginia Tech. New data and analysis tools are added regularly.
Pathogen Portal's Infectious Disease Triangle perspective supports an integrative understanding of human disease through the study of multiple levels of interactions between a susceptible Host, an infectious Pathogen, and a conducive (to disease) Environment. Originating from plant pathology, this ecological approach is increasingly relevant to health sciences. Because some diseases include invertebrate Vectors as part of their ecology, the Disease Triangle broadly considers Environment to include Vectors.

New data and analysis tools are added regularly to Pathogen Portal.